Compile Data Set for Download or QSAR
maximum 50k data
Found 370 of ec50 for UniProtKB: P26662
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516578(US11053243, Example 189b | methyl [(2S)-1-{(2S)-2-...)
Affinity DataEC50:  0.00100nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50147212(CHEMBL3765311 | US11053243, Example 192)
Affinity DataEC50:  0.00200nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516573(US11053243, Example 159 | tert-butyl {(1R)-2-[(2S)...)
Affinity DataEC50:  0.00200nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516583(US11053243, Example 203)
Affinity DataEC50:  0.00400nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516574(US11053243, Example 169 | tert-butyl {(1R)-2-[(2S)...)
Affinity DataEC50:  0.00400nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516552((2S,2'S)-N,N'-6,11-dihydro-5H- benzo[a]carbazole-3...)
Affinity DataEC50:  0.00600nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516568(US11053243, Example 137 | tert-butyl {(1R)-2-[(2S)...)
Affinity DataEC50:  0.00900nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516584(US11053243, Example 213)
Affinity DataEC50:  0.00900nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516553((2S,2'S)-N,N'-5,6,7,12- tetrahydrobenzo[6,7]cycloh...)
Affinity DataEC50:  0.0100nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516563(US11053243, Example 119 | propan-2-yl [(1R)-2-oxo-...)
Affinity DataEC50:  0.0130nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516554(N-(6,11-dihydro-5H- benzo[a]carbazol-3-yl)-1-{(2S)...)
Affinity DataEC50:  0.0150nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516576(US11053243, Example 186 | tert-butyl {(1S)-2-[(2S)...)
Affinity DataEC50:  0.0150nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516564(US11053243, Example 125 | tert-butyl [(1R)-2-{(2S)...)
Affinity DataEC50:  0.0160nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516580(US11053243, Example 191)
Affinity DataEC50:  0.0200nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516546((2S)-1-[(2R)-2-phenyl-2- (pyrrolidin-1-yl)acetyl]-...)
Affinity DataEC50:  0.0200nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516543(US11053243, Example 40 | di-tert-butyl (1H,1′...)
Affinity DataEC50:  0.0260nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516556(US11053243, Example 100 | benzyl (2S)-2-[5-(4-{5-[...)
Affinity DataEC50:  0.0310nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516570(US11053243, Example 144 | tert-butyl (2S)-2-[(3-fl...)
Affinity DataEC50:  0.0360nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516555(US11053243, Example 99 | tert-butyl {(1R)-2-[(2S)-...)
Affinity DataEC50:  0.0380nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516561(US11053243, Example 107 | tert-butyl {(1R)-2-[(2S)...)
Affinity DataEC50:  0.0400nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516538(US11053243, Example 15 | tert-butyl {(1R)-2-[(2S)-...)
Affinity DataEC50:  0.0450nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516566(US11053243, Example 130 | tert-butyl {(1S)-2-[(2S)...)
Affinity DataEC50:  0.0500nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516544(US11053243, Example 41 | tert-butyl {(1R)-2-oxo-1-...)
Affinity DataEC50:  0.0500nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516582((2R)-2-(diethylamino)-1- [(2S)-2-(5-{4-[5-(2-{(2S)...)
Affinity DataEC50:  0.0500nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516540((2S)-1-[(2R)-2-(diethylamino)-2- phenylacetyl]-N-(...)
Affinity DataEC50:  0.0630nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516562(N-(methoxycarbonyl)-L-valyl-N- {2-[4-(2-{(2S)-1-[N...)
Affinity DataEC50:  0.0650nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516579(US11053243, Example 190)
Affinity DataEC50:  0.0670nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516550((2S)-1-[(2R)-2-(diethylamino)-2- phenylacetyl]-N-(...)
Affinity DataEC50:  0.0670nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516547((2S)-1-(2,3-diphenylpropanoyl)- N-{4-[5-({[(2S)-1-...)
Affinity DataEC50:  0.0720nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516560(US11053243, Example 105 | tert-butyl{(1R)-2-[(2S)-...)
Affinity DataEC50:  0.0800nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244736(US10226449, cpd 346 | US9428502, 346)
Affinity DataEC50:  0.100nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516549((2S)-1-[(2R)-2phenyl-2- (piperidin-1-yl)acetyl]-N-...)
Affinity DataEC50:  0.130nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516577(US11053243, Example 189a | methyl [(2S)-1-{(2S)-2-...)
Affinity DataEC50:  0.150nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516551((2S)-1-[(2R)-2-(dimethylamino)- 2-phenylacetyl]-N-...)
Affinity DataEC50:  0.170nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516542((2S,2′S) N,N′,1H,1′H-2,2′-...)
Affinity DataEC50:  0.240nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516572(US11053243, Example 158 | tert-butyl {(1R)-2-[(2S)...)
Affinity DataEC50:  0.5nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516557(1-[(2R)-2-(dimethylamino)-2- phenylacetyl]-N-{2-[4...)
Affinity DataEC50:  0.5nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516565((2S)-N-{4-[3-fluoro-5-({[(2S)-1- (phenylacetyl)pyr...)
Affinity DataEC50:  0.700nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516571((2S) N-{4-[3-cyano-5-({[(2S)-1-(phenylacetyl)pyrro...)
Affinity DataEC50:  0.900nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516548(N-{2-[4-(acetylamino)phenyl]- 1H-indol-5-yl}-1[(2R...)
Affinity DataEC50:  0.970nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244632(US10226449, cpd 241 | US9428502, 241)
Affinity DataEC50: <1nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244629(US10226449, cpd 238 | US9428502, 238)
Affinity DataEC50:  1nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244563(US10226449, cpd 172 | US9428502, 172)
Affinity DataEC50:  1nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244568(US10226449, cpd 177 | US9428502, 177)
Affinity DataEC50:  1nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244534(US10226449, cpd 143 | US9428502, 143)
Affinity DataEC50:  2nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244738(US10226449, cpd 348 | US9428502, 348)
Affinity DataEC50:  2nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244624(US10226449, cpd 233 | US9428502, 233)
Affinity DataEC50:  2nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244436(US10226449, cpd 45 | US9428502, 45)
Affinity DataEC50:  2nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244555(US10226449, cpd 164 | US9428502, 164)
Affinity DataEC50:  2nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244575(US10226449, cpd 184 | US9428502, 184)
Affinity DataEC50:  2nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 370 total ) | Next | Last >>
Jump to: