Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of ki for UniProtKB: P09483
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM184561(US9150581, RTI-7527-(+/-)-102 | US9150581, RTI-752...)
Affinity DataKi:  0.00900nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM184561(US9150581, RTI-7527-(+/-)-102 | US9150581, RTI-752...)
Affinity DataKi:  0.0210nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM184561(US9150581, RTI-7527-(+/-)-102 | US9150581, RTI-752...)
Affinity DataKi:  0.0220nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50395218(CHEMBL2164666 | US9150581, RTI-7527-192)
Affinity DataKi:  0.0300nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM86805(CAS_45263788 | NSC_45263788 | US9150581, RTI-7527-...)
Affinity DataKi:  0.0730nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50395220(CHEMBL2164664 | US9150581, RTI-7527-(+/-)-154)
Affinity DataKi:  0.0800nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50395220(CHEMBL2164664 | US9150581, RTI-7527-(+/-)-154)
Affinity DataKi:  0.0820nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50395217(CHEMBL2164667 | US9150581, RTI-7527-168)
Affinity DataKi:  0.120nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50395220(CHEMBL2164664 | US9150581, RTI-7527-(+/-)-154)
Affinity DataKi:  0.170nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50171007(4-[5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-2-fluoro-pyri...)
Affinity DataKi:  0.190nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM86806(CAS_45263762 | NSC_45263762 | US9150581, RTI-7527-...)
Affinity DataKi:  0.240nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM86806(CAS_45263762 | NSC_45263762 | US9150581, RTI-7527-...)
Affinity DataKi:  0.240nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM86806(CAS_45263762 | NSC_45263762 | US9150581, RTI-7527-...)
Affinity DataKi:  0.260nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM184563(US9150581, RTI-7527-169)
Affinity DataKi:  0.360nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50395221(CHEMBL2164663 | US9150581, RTI-7527-153)
Affinity DataKi:  0.440nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM184560(US9150581, RTI-7527-107)
Affinity DataKi:  0.530nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute

US Patent
LigandPNGBDBM50395219(CHEMBL2164665 | US9150581, RTI-7527-193)
Affinity DataKi:  0.940nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
In DepthDetails US Patent