BindingDB PrimarySearch

Found 112 with your filter

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581180(CHEMBL5081214)

IC50: 0.100nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581182(CHEMBL5080391)

IC50: 0.126nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581183(CHEMBL5087564)

IC50: 0.158nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581184(CHEMBL5094110)

IC50: 0.251nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581185(CHEMBL5076558)

IC50: 0.316nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581181(CHEMBL5086895)

IC50: 0.316nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581179(CHEMBL5078680)

IC50: 1nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50581186(CHEMBL5088742)

IC50: 1nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

O43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

BDBM50492928(CHEMBL2414311)

IC50: 2.20nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

O43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

BDBM50399897(CHEMBL2180942)

IC50: 7.40nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

O43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

BDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)

IC50: 9.5nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details PubMed

O43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

BDBM50126469((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-((R)-1-propyl-...)

IC50: >10nMAssay Description:Inhibitory activity against phosphodiesterase 6 (PDE6) obtained from canine or bovine retinaMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

O43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

BDBM14776(2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phen...)

IC50: 11nMAssay Description:Inhibition of human phosphodiesterase 6More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

Purchase CHEMBL MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50019865(CHEMBL3286929)

IC50: 21nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529743(CHEMBL4440294)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529743(CHEMBL4440294)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50019865(CHEMBL3286929)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529737(CHEMBL4459864)

IC50: 24nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529737(CHEMBL4459864)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529736(CHEMBL4555739)

IC50: 25nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529732(CHEMBL4527667)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529736(CHEMBL4555739)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529732(CHEMBL4527667)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529734(CHEMBL4532027)

IC50: 26nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529734(CHEMBL4532027)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529745(CHEMBL4548659)

IC50: 27nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529738(CHEMBL4514611)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529738(CHEMBL4514611)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529745(CHEMBL4548659)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

O43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

BDBM50241831(CHEMBL4062273 | US10626113, Compound M | US1089975...)

IC50: 30nMAssay Description:Inhibition of PDE6 (unknown origin) using FAM-cGMP or FAM-cAMP as substrate incubated for 60 mins and measured by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529740(CHEMBL4536719)

IC50: 30nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529740(CHEMBL4536719)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529749(CHEMBL4440110)

IC50: 33nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529749(CHEMBL4440110)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529746(CHEMBL4589625)

IC50: 34nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529746(CHEMBL4589625)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529744(CHEMBL4588289)

IC50: 35nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529744(CHEMBL4588289)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529731(CHEMBL4566147)

IC50: 37nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529731(CHEMBL4566147)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529733(CHEMBL4585643)

IC50: 39nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529733(CHEMBL4585643)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529730(CHEMBL4443518)

IC50: 40nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

O43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL

BDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)

IC50: 40nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529730(CHEMBL4443518)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529747(CHEMBL4449262)

IC50: 41nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529735(CHEMBL4439169)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529747(CHEMBL4449262)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529735(CHEMBL4439169)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL

BDBM50529752(CHEMBL4443194)

IC50: 43nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Displayed 1 to 50 (of 112 total ) | Next | Last >>

Filter my 349 hits

Targets 2▿
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 296
- O43924/P16499/P18545/P35913/P51160/Q13956 53
Publications 24▿
- US Patent US10913710 (2021) 100
- J Med Chem 57: 5435-48 (2014) 53
- Eur J Med Chem 163: 597-609 (2019) 52
- J Med Chem 61: 2604-2610 (2018) 30
- J Med Chem 60: 9400-9406 (2017) 19
- Bioorg Med Chem Lett 13: 1425-8 (2003) 19
- J Med Chem 63: 7892-7905 (2020) 14
- ACS Med Chem Lett 13: 298-303 (2022) 14
- J Med Chem 49: 5363-71 (2006) 12
- J Med Chem 64: 9100-9119 (2021) 8
- J Med Chem 48: 3449-62 (2005) 5
- Eur J Med Chem 229: (2022) 4
- J Med Chem 62: 4370-4382 (2019) 3
- Bioorg Med Chem Lett 23: 4944-7 (2013) 3
- Eur J Med Chem 232: (2022) 2
- Bioorg Med Chem Lett 44: (2021) 2
- Bioorg Med Chem 56: (2022) 2
- J Med Chem 65: 7489-7531 (2022) 1
- J Med Chem 57: 6632-41 (2014) 1
- Bioorg Med Chem Lett 26: 4216-22 (2016) 1
- Bioorg Med Chem Lett 30: (2020) 1
- Bioorg Med Chem 27: 3440-3450 (2019) 1
- Bioorg Med Chem Lett 14: 1577-80 (2004) 1
- ACS Med Chem Lett 12: 302-308 (2021) 1
Institutions 20▿
- Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften 100
- Second Military Medical University 77
- Chinese Academy Of Sciences 55
- Max Planck Institute Of Molecular Physiology 53
- Pfizer 19
- Università 12
- Chiesi Farmaceutici 8
- Monash University (Parkville Campus) 5
- Central South University 4
- TBA 3
- Indian Institute Of Technology (B.H.U.) 2
- Shaoxing University 2
- Merck 2
- Mitsubishi Tanabe Pharma 1
- Janssen Research & Development 1
- Amgen 1
- Astrazeneca 1
- Changzhou University 1
- University College London 1
- Bristol-Myers Squibb Pharmaceutical Research Institute 1
Affinity: 0.077 to 1.0E+5 nM▿
- Ki 17
- IC50 112
- Kd 220
- Affinity ≤ nM
Xtal structures: 12
Docked structures: 0
Catalog Cmpds: 70