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IC50: 5.00E+4nM Assay Description: Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor More data for this Ligand-Target Pair
Filter my 16 hits
Targets 5▿
Nucleotide-binding oligomerization domain-containing protein 1 5
Nucleotide-binding oligomerization domain-containing protein 2 5
Interleukin-8 3
Tumor necrosis factor 2
Son of sevenless homolog 1 1
Publications 10▿
ACS Med Chem Lett 2: 780 -785 (2011) 2 PubChem Bioassay (2010) 2 PubChem Bioassay (2010) 2 PubChem Bioassay (2010) 2 Bioorg Med Chem 24: 5221 -5234 (2016) 2 J Med Chem 57: 6897 -918 (2014) 2 J Med Chem 63: 8325 -8337 (2020) 1 PubChem Bioassay (2010) 1 PubChem Bioassay (2010) 1 PubChem Bioassay (2010) 1
Institutions 4▿
Burnham Center For Chemical Genomics 9 University Of Ljubljana 4 TBA 2 Vanderbilt University School Of Medicine 1
Affinity: 4.6E+3 to 3.5E+5 nM▿
Xtal structures: 1
Docked structures: 0 Catalog Cmpds: 1