Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 7970
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226157(PTP1B spring 7 (7))
Affinity DataKi:  3.00E+3nM ΔG°:  -32.8kJ/mole IC50:  4.80E+3nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
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TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226153(Selaginellin U (2))
Affinity DataKi:  9.70E+3nM ΔG°:  -29.8kJ/mole IC50:  1.38E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226155(Selaginellin W (4))
Affinity DataKi:  1.11E+4nM ΔG°:  -29.4kJ/mole IC50:  1.46E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
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TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226154(Selaginellin V (3))
Affinity DataKi:  1.13E+4nM ΔG°:  -29.4kJ/mole IC50:  1.45E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
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TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226156(PTP1B spring 5 (5))
Affinity DataKi:  1.39E+4nM ΔG°:  -28.8kJ/mole IC50:  1.59E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataKi:  1.45E+4nM ΔG°:  -28.7kJ/mole IC50:  1.32E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  4.50E+3nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Catholic University of Daegu

LigandPNGBDBM226152(Selaginellin T (1))
Affinity DataIC50:  5.80E+4nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails