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Found 17 Enz. Inhib. hit(s) with all data for entry = 50035177
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  3nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 8 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards L100I mutant HIV-1 reverse transcriptase (as per ref 10 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataKi:  17nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 6 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50105629(CHEMBL54893 | N-(4-chloro-3-(3-methylbut-2-enyloxy...)
Affinity DataEC50:  9nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  53nMAssay Description:Binding affinity towards wild type HIV-1 reverse transcriptase (as per ref 10 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  70nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 6 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50105629(CHEMBL54893 | N-(4-chloro-3-(3-methylbut-2-enyloxy...)
Affinity DataEC50:  24nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 7 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataEC50:  5.60E+3nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 7 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  380nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 12 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2337(6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-...)
Affinity DataEC50:  2nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  26nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 7 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  100nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 12 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  20nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 12 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  30nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 8 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2337(6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-...)
Affinity DataEC50:  20nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataEC50:  60nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataEC50:  110nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 6 in the article)More data for this Ligand-Target Pair