Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50008473
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073686(CHEMBL423029 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  0.440nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  0.450nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073684(2-(5-tert-Butyl-1H-indol-3-yl)-ethylamine | CHEMBL...)
Affinity DataKi:  0.600nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073687(2-(5-Isopropyl-1H-indol-3-yl)-ethylamine | CHEMBL1...)
Affinity DataKi:  1.10nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073681(2-(5-Cyclopentyl-1H-indol-3-yl)-ethylamine | CHEMB...)
Affinity DataKi:  1.70nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  1.90nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  2nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073682(CHEMBL1278 | N-methyl-2-(3-(1-methylpiperiden-4-yl...)
Affinity DataKi:  2.30nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073682(CHEMBL1278 | N-methyl-2-(3-(1-methylpiperiden-4-yl...)
Affinity DataKi:  3.30nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073690(2-(5-Cyclohexyl-1H-indol-3-yl)-ethylamine | CHEMBL...)
Affinity DataKi:  3.40nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049086(2-(5-Ethyl-1H-indol-3-yl)-ethylamine | CHEMBL10751...)
Affinity DataKi:  3.70nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataKi:  4.30nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073689((R)-6-Methylamino-6,7,8,9-tetrahydro-5H-carbazole-...)
Affinity DataKi:  4.40nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  4.40nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  6.10nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073685(CHEMBL147454 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  6.20nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073691(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)
Affinity DataKi:  6.40nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  9.60nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataKi:  10.1nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073689((R)-6-Methylamino-6,7,8,9-tetrahydro-5H-carbazole-...)
Affinity DataKi:  10.3nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073683(CHEMBL343025 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataKi:  10.8nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073682(CHEMBL1278 | N-methyl-2-(3-(1-methylpiperiden-4-yl...)
Affinity DataKi:  45nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073689((R)-6-Methylamino-6,7,8,9-tetrahydro-5H-carbazole-...)
Affinity DataKi:  62nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataKi:  140nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  230nMAssay Description:In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataEC50:  4.30nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase in a cell line expressing human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073682(CHEMBL1278 | N-methyl-2-(3-(1-methylpiperiden-4-yl...)
Affinity DataEC50:  1.60nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase in a cell line expressing human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073688(CHEMBL357034 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...)
Affinity DataEC50:  0.220nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase in a cell line expressing human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50033437(CHEMBL905 | MK 462 free base | N,N-dimethyl-2-[5-(...)
Affinity DataEC50:  3nMAssay Description:Ability to inhibit forskolin-stimulated adenylate cyclase in a cell line expressing human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank