Found 39 Enz. Inhib. hit(s) with all data for entry = 50012272 
Affinity DataKi: 0.540nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 0.54/59)More data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 9.0/1800)More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 8.5nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 25/1600)More data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]-pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity of compound measured against Dopamine receptor D1 from bovine striatal membranes using radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Effective concentration required for agonistic activity against human Dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 27/1800)More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 27/5400)More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 35/3700)More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 8.5/130)More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 50/2200)More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]-pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 87/23000)More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 130/50000)More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 16/16000)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Binding affinity of compound measured for 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT-labeled porcine brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]-pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:Binding affinity of compound measured against Dopamine receptor D1 from bovine striatal membranes using radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
Affinity DataEC50: 9.80nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]-pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 9.20nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 430nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 0.87/44)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 47nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 16/1300)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 230/53000)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D2L (high/low affinity is given as 85/6400)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 40/3600)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Effective concentration required for agonistic activity against rat Dopamine receptor D2LMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
