TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 5.20E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 4.14E+4nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.24E+4nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.90E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 7.00E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.73E+4nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.60E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 4.10E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 2.78E+4nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 800nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.40E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.24E+4nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 9.80E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 6.60E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.19E+4nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 5.20E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair