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Found 17 Enz. Inhib. hit(s) with all data for entry = 50018516
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196604(CHEMBL217083 | N-hydroxy-7-(naphthalen-2-yloxy)hep...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196608(7-(4-((4-chlorobenzyl)(methyl)amino)phenoxy)-N-hyd...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196600(7-(1H-indol-5-yloxy)-N-hydroxyheptanamide | CHEMBL...)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196598(7-(4-(3-(1H-indol-3-yl)prop-1-en-2-ylamino)phenyl1...)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196605(7-(4-(2-(1H-indol-3-yl)acetamido)phenyl1H-indol-3-...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196603(7-(4-(2-(1H-indol-3-yl)acetamido)-2-fluorophenyl1H...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196594(7-(4-((1H-indol-5-yl)methylamino)phenyl1H-indol-5-...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196597(CHEMBL384714 | N-hydroxy-7-(4-(methyl(pyridin-4-yl...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196609(7-(4-(3-(1H-indol-3-yl)propanamido)phenyl1H-indol-...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196607(7-(4-(3-(1H-indol-3-yl)-N-(pyridin-4-ylmethyl)prop...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196602(7-(4-(dimethylamino)phenoxy)-N-hydroxyheptanamide ...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196601(CHEMBL217778 | N-hydroxy-7-(4-(4-methoxyphenylsulf...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196596(8-(4-(2-(1H-indol-3-yl)acetamido)phenyl1H-indol-3-...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196593(CHEMBL387042 | N-hydroxy-7-(4-((3-hydroxy-5-(hydro...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196606(7-(4-(2-(1H-indol-3-yl)acetamido)-3-fluorophenyl1H...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196595(6-(4-(2-(1H-indol-3-yl)acetamido)phenyl1H-indol-3-...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196599(7-(3-fluoro-4-((3-hydroxy-5-(hydroxymethyl)-2-meth...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed