Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50018599
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM31459(CHEMBL224485 | substituted biphenyl derivative, 21)
Affinity DataIC50:  89nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197327(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-{[...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197325(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197331(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-({...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197330(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197324(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197326(2'-(3-carbamoyl-phenylcarbamoyl)-4-isobutylcarbamo...)
Affinity DataIC50:  690nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197329(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50:  860nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM31459(CHEMBL224485 | substituted biphenyl derivative, 21)
Affinity DataIC50:  880nMAssay Description:Inhibition of human Fxa by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197340(2'-({[4-(aminomethyl)phenyl]amino}carbonyl)-4-({[(...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197336(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197341(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-{[...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197333(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-[(...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197334(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-[(...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197332(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}carb...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197338(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-{[...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197339(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-{[...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197335(2'-(3-Carbamoyl-phenylcarbamoyl)-4-isobutylcarbamo...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197328(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197337(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-({...)
Affinity DataIC50:  1.91E+5nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197327(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-{[...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197326(2'-(3-carbamoyl-phenylcarbamoyl)-4-isobutylcarbamo...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197325(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human Fxa by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197327(2'-({[3-(aminocarbonyl)phenyl]amino}carbonyl)-4-{[...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human Fxa by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197324(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human Fxa by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197324(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197325(4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}-car...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM31459(CHEMBL224485 | substituted biphenyl derivative, 21)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50197326(2'-(3-carbamoyl-phenylcarbamoyl)-4-isobutylcarbamo...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human Fxa by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed