Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50027621
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254809((R)-(7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropy...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254617(7-(3,4-dichlorophenyl)-5-methyl-N,N-dipropyl-4,7-d...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254736((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254698(5-(1-cyclohexylvinyl)-4-(3,4-dimethylphenyl)-6-met...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254656(7-(3,4-dichlorophenyl)-5-methyl-N-phenethyl-4,7-di...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254929((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254966((7-(3,5-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254737((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  159nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254926((7-(2,3-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254850((7-(benzofuran-2-yl)-5-methyl-4,7-dihydropyrazolo[...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254808((S)-(7-(2,3-dichlorophenyl)-5-methyl-4,7-dihydropy...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254655(CHEMBL465086 | N-benzyl-7-(3,4-dichlorophenyl)-5-m...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254654(7-(3,4-dichlorophenyl)-5-methyl-N-phenyl-4,7-dihyd...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254699(CHEMBL518718 | azepan-1-yl(7-(3,4-dichlorophenyl)-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254890((7-(3-chlorophenyl)-5-methyl-4,7-dihydropyrazolo[1...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254849((4-(4-fluorophenyl)piperazin-1-yl)(5-methyl-7-(3-m...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254778((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254807((7-(5-chlorothiophen-2-yl)-5-methyl-4,7-dihydropyr...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254927((7-(2,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254618(CHEMBL520917 | N,N-dibutyl-7-(3,4-dichlorophenyl)-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254998((7-(3,5-dimethylphenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254616(7-(3,4-dichlorophenyl)-N,N-diethyl-5-methyl-4,7-di...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254891((7-(4-chlorophenyl)-5-methyl-4,7-dihydropyrazolo[1...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254614(CHEMBL481396 | N-butyl-7-(3,4-dichlorophenyl)-5-me...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254479(7-(3,4-dichlorophenyl)-5-methyl-N-propyl-4,7-dihyd...)
Affinity DataIC50:  490nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254967((4-(4-fluorophenyl)piperazin-1-yl)(5-methyl-7-m-to...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254653(7-(3,4-dichlorophenyl)-5-methyl-N,N-dipentyl-4,7-d...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254615(7-(3,4-dichlorophenyl)-5-methyl-N-pentyl-4,7-dihyd...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254437((4-(4-fluorophenyl)piperazin-1-yl)(5-methyl-7-(nap...)
Affinity DataIC50:  650nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254697((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254997((7-(3,4-dimethylphenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254928((7-(2,5-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254696(CHEMBL518717 | azetidin-1-yl(7-(3,4-dichlorophenyl...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50254777(CHEMBL481187 | ethyl 7-(2,3-dichlorophenyl)-5-meth...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50000778((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed