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Found 71 Enz. Inhib. hit(s) with all data for entry = 50029923
LigandPNGBDBM50289368(Butane-1-sulfonic acid [3-(2,3-dibromo-5-oxo-5,6-d...)
Affinity DataIC50:  85nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289368(Butane-1-sulfonic acid [3-(2,3-dibromo-5-oxo-5,6-d...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289353(2,3-Dibromo-8-(4-methoxy-phenyl)-6H-imidazo[1,2-d]...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289357(1-Butyl-3-[3-(2,3-dibromo-5-oxo-5,6-dihydro-imidaz...)
Affinity DataIC50:  650nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289360(2,3-Dibromo-8-phenyl-6H-imidazo[1,2-d][1,2,4]triaz...)
Affinity DataIC50:  770nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289361(Butane-1-sulfonic acid [4-(2,3-dibromo-5-oxo-5,6-d...)
Affinity DataIC50:  840nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289367(8-(4-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1...)
Affinity DataIC50:  910nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289350(1-Butyl-3-[2-(2,3-dibromo-5-oxo-5,6-dihydro-imidaz...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289355(8-(2-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289361(Butane-1-sulfonic acid [4-(2,3-dibromo-5-oxo-5,6-d...)
Affinity DataIC50:  1.02E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289353(2,3-Dibromo-8-(4-methoxy-phenyl)-6H-imidazo[1,2-d]...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289358(8-(3-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1...)
Affinity DataIC50:  1.15E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289357(1-Butyl-3-[3-(2,3-dibromo-5-oxo-5,6-dihydro-imidaz...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289354(CHEMBL426946 | N-[3-(2,3-Dibromo-5-oxo-5,6-dihydro...)
Affinity DataIC50:  1.22E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289367(8-(4-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289362(2,3-Dibromo-8-cyclohexyl-6H-imidazo[1,2-d][1,2,4]t...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289361(Butane-1-sulfonic acid [4-(2,3-dibromo-5-oxo-5,6-d...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289356(1-Butyl-3-[4-(2,3-dibromo-5-oxo-5,6-dihydro-imidaz...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289366(CHEMBL366491 | N-[4-(2,3-Dibromo-5-oxo-5,6-dihydro...)
Affinity DataIC50:  1.82E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289360(2,3-Dibromo-8-phenyl-6H-imidazo[1,2-d][1,2,4]triaz...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289364(2,3-Dimethyl-8-phenyl-6H-imidazo[1,2-d][1,2,4]tria...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289366(CHEMBL366491 | N-[4-(2,3-Dibromo-5-oxo-5,6-dihydro...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289351(2,3-Dibromo-8-phenyl-6H-imidazo[1,2-d][1,2,4]triaz...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289358(8-(3-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289360(2,3-Dibromo-8-phenyl-6H-imidazo[1,2-d][1,2,4]triaz...)
Affinity DataIC50:  2.90E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289368(Butane-1-sulfonic acid [3-(2,3-dibromo-5-oxo-5,6-d...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289369(3-Bromo-8-phenyl-6H-imidazo[1,2-d][1,2,4]triazin-5...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289364(2,3-Dimethyl-8-phenyl-6H-imidazo[1,2-d][1,2,4]tria...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289362(2,3-Dibromo-8-cyclohexyl-6H-imidazo[1,2-d][1,2,4]t...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289365(2,3-Dibromo-8-pyridin-4-yl-6H-imidazo[1,2-d][1,2,4...)
Affinity DataIC50:  3.60E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289362(2,3-Dibromo-8-cyclohexyl-6H-imidazo[1,2-d][1,2,4]t...)
Affinity DataIC50:  3.90E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289351(2,3-Dibromo-8-phenyl-6H-imidazo[1,2-d][1,2,4]triaz...)
Affinity DataIC50:  3.90E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289352(2,3-Dichloro-8-phenyl-6H-imidazo[1,2-d][1,2,4]tria...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289354(CHEMBL426946 | N-[3-(2,3-Dibromo-5-oxo-5,6-dihydro...)
Affinity DataIC50:  4.40E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289356(1-Butyl-3-[4-(2,3-dibromo-5-oxo-5,6-dihydro-imidaz...)
Affinity DataIC50:  4.50E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289365(2,3-Dibromo-8-pyridin-4-yl-6H-imidazo[1,2-d][1,2,4...)
Affinity DataIC50:  4.60E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)
Affinity DataIC50:  6.00E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289359(8-Phenyl-6H-imidazo[1,2-d][1,2,4]triazin-5-one | C...)
Affinity DataIC50:  6.40E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289352(2,3-Dichloro-8-phenyl-6H-imidazo[1,2-d][1,2,4]tria...)
Affinity DataIC50:  8.50E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289354(CHEMBL426946 | N-[3-(2,3-Dibromo-5-oxo-5,6-dihydro...)
Affinity DataIC50:  9.70E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289363(2,3-Dibromo-6-methyl-8-phenyl-6H-imidazo[1,2-d][1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14362(6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289355(8-(2-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289350(1-Butyl-3-[2-(2,3-dibromo-5-oxo-5,6-dihydro-imidaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289359(8-Phenyl-6H-imidazo[1,2-d][1,2,4]triazin-5-one | C...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289350(1-Butyl-3-[2-(2,3-dibromo-5-oxo-5,6-dihydro-imidaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289359(8-Phenyl-6H-imidazo[1,2-d][1,2,4]triazin-5-one | C...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289363(2,3-Dibromo-6-methyl-8-phenyl-6H-imidazo[1,2-d][1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
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