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Found 19 Enz. Inhib. hit(s) with all data for entry = 50048337
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212861(CHEMBL49545)
Affinity DataEC50: >2.60E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212892(CHEMBL48059)
Affinity DataEC50:  6.20E+4nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212863(CHEMBL45881)
Affinity DataEC50:  5.00E+4nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataEC50: >2.80E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212864(CHEMBL49666)
Affinity DataEC50: >2.90E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataEC50:  810nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212865(CHEMBL45755)
Affinity DataEC50:  5.10E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212866(CHEMBL542357)
Affinity DataEC50: >5.60E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212867(CHEMBL50551)
Affinity DataEC50: >5.40E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212868(CHEMBL43881)
Affinity DataEC50:  7.30E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212869(CHEMBL45887)
Affinity DataEC50: >5.70E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212870(CHEMBL45923)
Affinity DataEC50:  5.80E+4nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212871(CHEMBL49381)
Affinity DataEC50:  4.20E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212888(CHEMBL299989)
Affinity DataEC50:  9.40E+3nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212889(CHEMBL45605)
Affinity DataEC50: >1.30E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212890(CHEMBL298368)
Affinity DataEC50:  3.10E+4nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212891(CHEMBL295775)
Affinity DataEC50:  1.50E+5nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212862(CHEMBL296812)
Affinity DataEC50:  5.70E+4nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails