Affinity DataIC50: 560nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.03E+3nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PIM1 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant PIM1 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant PIM1 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.19E+4nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.78E+4nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 530nMAssay Description:Binding affinity to C-terminal kinase domain 2 of RPS6KA1More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 290nMAssay Description:Binding affinity to JH domain of TYK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 2.40E+4nMAssay Description:Binding affinity to ULK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 32B(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to YANK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 220nMAssay Description:Binding affinity to YSK4More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to CDKL5More data for this Ligand-Target Pair
Affinity DataKd: 7.50E+3nMAssay Description:Binding affinity to CDK7More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to CAMKK1More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to CAMK2GMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 720nMAssay Description:Binding affinity to BMPR1BMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Binding affinity to AAK1More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair