Found 121 Enz. Inhib. hit(s) with all data for entry = 50006566 
Affinity DataKi: 4.40E+4nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Binding affinity towards mGluR1a was determinedMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 5.00E+4nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 2.05E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataKi: >2.80E+5nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonistic activity against mGluR2 was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP formation in BHK cells expressing mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP formation in BHK cells expressing mGluR4More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR4More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
