Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50018485
LigandPNGBDBM50608647(CHEMBL5267724)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608649(CHEMBL5290499)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608646(CHEMBL5288936)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608648(CHEMBL5286715)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50518950(CHEMBL4468881)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608650(CHEMBL5271348)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608668(CHEMBL5282942)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608666(CHEMBL5267457)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608645(CHEMBL4535844)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608667(CHEMBL5271201)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608644(CHEMBL4570053)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608643(CHEMBL5274431)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608657(CHEMBL5278136)
Affinity DataIC50:  14nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50198237(CHEMBL3898662)
Affinity DataIC50:  58nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50198240(CHEMBL3908487)
Affinity DataIC50:  58nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608663(CHEMBL5272532)
Affinity DataIC50:  73nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608655(CHEMBL5280982)
Affinity DataIC50:  120nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608662(CHEMBL5284259)
Affinity DataIC50:  140nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50174319(CHEMBL3809184)
Affinity DataIC50:  180nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50608669(CHEMBL3884935)
Affinity DataIC50:  510nMAssay Description:Inhibition of Mycobacterium tuberculosis (MTB) DNA gyrase using pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608653(CHEMBL5281268)
Affinity DataIC50:  619nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608642(CHEMBL5290948)
Affinity DataIC50:  750nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50608671(CHEMBL3883383)
Affinity DataIC50:  770nMAssay Description:Inhibition of Mycobacterium tuberculosis (MTB) DNA gyrase using pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50608670(CHEMBL3883797)
Affinity DataIC50:  820nMAssay Description:Inhibition of Mycobacterium tuberculosis (MTB) DNA gyrase using pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608654(CHEMBL5267215)
Affinity DataIC50:  970nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608656(CHEMBL5271712)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608658(CHEMBL5272437)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)TBA
LigandPNGBDBM166663(N-(4-(4-Hydrazinyl-4-oxobutanamido)phenyl)-5-methy...)
Affinity DataIC50:  5.35E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseB ATPase activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608659(CHEMBL5285496)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM166646(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608651(CHEMBL3906178)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50249787(CHEMBL4752218)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50045000((NFLX)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50608661(CHEMBL5286132)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608660(CHEMBL5272158)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608652(CHEMBL5281739)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50608665(CHEMBL4637080)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50608664(CHEMBL5280084)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed