Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 702
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5148((2E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-{3-[(2E)-3-...)
Affinity DataIC50:  340nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5164((2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxyphenyl)eth-1...)
Affinity DataIC50:  380nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5149((2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  400nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5150((2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  500nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5151((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  600nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5152((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydrox...)
Affinity DataIC50:  600nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5153((2E)-2-cyano-N-{5-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  700nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5154((2E)-2-cyano-N-{6-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  700nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5165((2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-{[(1E)-2-(3...)
Affinity DataIC50:  850nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5166((2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxy-5-methoxyph...)
Affinity DataIC50:  940nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5155((2E)-2-cyano-N-{10-[(2E)-2-cyano-3-(3,4-dihydroxyp...)
Affinity DataIC50:  1.30E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5156((2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxy...)
Affinity DataIC50:  1.60E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5157((2E)-2-cyano-N-[(3-{[(2E)-2-cyano-3-(3,4-dihydroxy...)
Affinity DataIC50:  1.80E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5159((2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  2.10E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5160((2E)-2-cyano-N-{8-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  2.20E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5161((2E)-2-cyano-N-(2-{4-[(2E)-2-cyano-2-[(3,4-dihydro...)
Affinity DataIC50:  2.20E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5162((2E)-2-({4-[(2E)-2-cyano-2-[(3,4-dihydroxyphenyl)m...)
Affinity DataIC50:  4.00E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5163((2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(1H-indol-5-yl)p...)
Affinity DataIC50: >1.00E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5158((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(4-hydroxy-3-met...)
Affinity DataIC50:  1.12E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed