Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1684
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13344(N-[4-Chloro-3-(3-pyridinyloxymethyl)phenyl]-3-fluo...)
Affinity DataIC50:  65nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13354(3-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-1-(4-chl...)
Affinity DataIC50:  196nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  290nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13353(3-fluoro-5-(morpholin-4-yl)-N-{1-[2-(pyridin-4-yl)...)
Affinity DataIC50:  340nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13345(1-(5-tert-Butyl-2H-pyrazol-3-yl)-3-[4-chloro-3-(py...)
Affinity DataIC50:  350nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13351(3-fluoro-5-(morpholin-4-yl)-N-{3-[2-(pyridin-4-yl)...)
Affinity DataIC50:  630nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13349(2-({4-[2-(1H-indol-3-yl)ethyl]pyrimidin-2-yl}amino...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13342(2-({5-[(2,6-dichlorophenyl)methoxy]pyridin-2-yl}am...)
Affinity DataIC50:  2.40E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13343(N-[4-Chloro-3-(3-pyridinyloxymethyl)phenyl]benzami...)
Affinity DataIC50:  3.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13346(3-(2-(4-Pyridyl)ethyl)indole | 3-[2-(pyridin-4-yl)...)
Affinity DataIC50:  3.50E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13340(2-Amino-3-(1-naphthylmethyloxy)pyridine | 3-(napht...)
Affinity DataIC50:  4.40E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13339(2-Amino-3-(2,6-dichlorobenzyloxy)pyridine | 3-[(2,...)
Affinity DataIC50:  1.09E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13348(3-[2-(2-chloropyrimidin-4-yl)ethyl]-1H-indole | In...)
Affinity DataIC50:  1.20E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13350(3-fluoro-N-(1H-indol-5-yl)-5-(morpholin-4-yl)benza...)
Affinity DataIC50:  1.62E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13352(1-(2-(4-Pyridyl)ethyl)indole | 1-[2-(pyridin-4-yl)...)
Affinity DataIC50:  1.85E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13341(2-({5-[(2,6-dichlorophenyl)methoxy]pyridin-2-yl}am...)
Affinity DataIC50:  2.00E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13347(3-(2-pyrimidin-4-ylethyl)-1H-indole | 3-[2-(pyrimi...)
Affinity DataIC50:  7.20E+5nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13338(3-(benzyloxy)pyridine | Pyridine derived fragment ...)
Affinity DataIC50:  1.00E+6nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astex

LigandPNGBDBM13337(3-(benzyloxy)pyridin-2-amine | EN300-247019 | Pyri...)
Affinity DataIC50:  1.30E+6nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair