Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 452
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2685(3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1...)
Affinity DataIC50:  5nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
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TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50:  10nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
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TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
Affinity DataIC50:  13nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
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TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
Affinity DataIC50:  26nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2692(3-(1H-indol-3-yl)-4-{1-[(1-methylpiperidin-3-yl)me...)
Affinity DataIC50:  45nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
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TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)
Affinity DataIC50:  52nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2693(3-(1H-indol-3-yl)-4-{1-[3-(morpholin-4-yl)propyl]-...)
Affinity DataIC50:  70nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2690(3-(1-{2-[(dimethylamino)methyl]propyl}-1H-indol-3-...)
Affinity DataIC50:  80nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2583(3,4-Bis(3-indolyl)-1H-pyrrole-2,5-dione | 3,4-bis(...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2682(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-[1...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2688(3-(1H-indol-3-yl)-4-[1-(2-methoxyethyl)-1H-indol-3...)
Affinity DataIC50:  200nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2680(3-(6-hydroxy-1H-indol-3-yl)-4-(1H-indol-3-yl)-2,5-...)
Affinity DataIC50:  200nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2687(Bisindolyl deriv. 13 | methyl 3-{3-[4-(1H-indol-3-...)
Affinity DataIC50:  200nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2684(3-[3-(dimethylamino)propyl]-3,13,23-triazahexacycl...)
Affinity DataIC50:  260nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2586(3,4-Bis(3-indolyl)-3-pyrrolin-2-one | 3,4-bis(1H-i...)
Affinity DataIC50:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2689(3-[1-(3-dymethylaminopropyl)-indol-3-yl]-4-(indol-...)
Affinity DataIC50:  2.75E+3nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2676(3,4-bis(1H-indol-3-yl)pyrrolidine-2,5-dione | Bisi...)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2587(5-Hydroxy-3,4-Bis(3-indolyl)-3-pyrrolin-2-one | 5-...)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2679(3,4-bis(2-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyr...)
Affinity DataIC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50: >2.50E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2672(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50:  4.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2588(3,4-bis(1H-indol-3-yl)-2,5-dihydrofuran-2,5-dione ...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2582(3,4-bis(1H-indol-3-yl)-1-methyl-2,5-dihydro-1H-pyr...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed