Compile Data Set for Download or QSAR
maximum 50k data
Found 262 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 11639
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM50073587(CHEMBL3408947 | US10358436, Example A185 | US20230...)
Affinity DataIC50:  43nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636140(5-methoxy-6-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  171nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636084((1R,2S)-2-(3-{[2-(dimethylamino)-6,7-dihydro-5H-cy...)
Affinity DataIC50:  196nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636053((1R,2S)-2-(3-{[2-(dimethylamino)-5-methylpyrimidin...)
Affinity DataIC50:  239nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636135((1R,2S)-5'-methoxy-2-(3-{[3-methoxy-5-(morpholine-...)
Affinity DataIC50:  242nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636141(5-methoxy-6-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  267nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636075(5-methoxy-6-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  278nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636014((1R,2R)-5'-fluoro-2-{7-fluoro-3-[(5-methoxy-2-meth...)
Affinity DataIC50:  297nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636070((1R,2S)-5'-methoxy-2-{3-[2-methoxy-4-(morpholine-4...)
Affinity DataIC50:  315nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636027((1R,2S)-5'-methoxy-2-(3-{[5-methoxy-2-(methylsulfa...)
Affinity DataIC50:  316nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636061(4-[5-methoxy-4-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2...)
Affinity DataIC50:  345nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636038((1R,2S)-5'-methoxy-2-(3-{[5-methoxy-2-(pyrrolidin-...)
Affinity DataIC50:  349nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635972((1R,2S)-5'-methoxy-2-(3-{[5-methoxy-2-(morpholin-4...)
Affinity DataIC50:  352nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635983((1R,2S)-2-(3-{[6-(3-hydroxyazetidin-1-yl)-2-(propa...)
Affinity DataIC50:  360nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636117((1R,2S)-5'-methoxy-2-(3-{[2-methoxy-6-(8-oxa-3-aza...)
Affinity DataIC50:  360nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636005((1R,2S)-5'-fluoro-2-{3-[(5-methoxy-2-methylpyrimid...)
Affinity DataIC50:  361nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636060((1R,2S)-2-(3-{[2-(4,4-difluoropiperidin-1-yl)-5-me...)
Affinity DataIC50:  401nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636080((1R,2S)-2-(3-{[6-(ethanesulfonyl)-2-methoxypyridin...)
Affinity DataIC50:  420nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636078((1R,2S)-2-{3-[5-fluoro-2-methoxy-4-(morpholine-4-c...)
Affinity DataIC50:  473nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636088((1R,2S)-5'-methoxy-2-{3-[(3-methoxy-1,5-naphthyrid...)
Affinity DataIC50:  495nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636077(2-fluoro-5-methoxy-4-({6-[(1R,2S)-5'-methoxy-2'-ox...)
Affinity DataIC50:  499nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635910((1R,2S)-5'-methoxy-2-(3-{[6-(3-methoxyazetidin-1-y...)
Affinity DataIC50:  506nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635935((1R,2S)-2-(3-((6-(1,1-dioxidothiomorpholino)-2-met...)
Affinity DataIC50:  513nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635996((1R,2S)-2-{3-[(5-methoxy-2-methylpyrimidin-4-yl)am...)
Affinity DataIC50:  516nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636036((1R,2S)-2-{3-[(2-chlorofuro[3,2-d]pyrimidin-4-yl)a...)
Affinity DataIC50:  521nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636114(N,N-dicyclopropyl-6-methoxy-5-({6-[(1R,2S)-5'-meth...)
Affinity DataIC50:  550nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636083(2,5-dimethoxy-4-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',...)
Affinity DataIC50:  560nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636023((1R,2S)-5'-methoxy-2-(3-{[2-methyl-6-(propan-2-yl)...)
Affinity DataIC50:  597nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635998((1R,2S)-2-{3-[(5-methoxy-2-methylpyrimidin-4-yl)am...)
Affinity DataIC50:  597nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636093(6-methoxy-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  606nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636030((1R,2S)-5'-methoxy-2-{3-[(2-methyl-6,7-dihydro-5H-...)
Affinity DataIC50:  608nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635913((1R,2S)-2-(3-{[6-(2-hydroxyethoxy)pyrimidin-4-yl]a...)
Affinity DataIC50:  616nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636081(5-methoxy-4-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  623nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636001((1R,2S)-4'-fluoro-2-{3-[(5-methoxy-2-methylpyrimid...)
Affinity DataIC50:  625nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635906((1R,2S)-5'-methoxy-2-{3-[(3-oxo-2,3-dihydro-1-benz...)
Affinity DataIC50:  625nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636032((1R,2S)-5'-methoxy-2-{3-[(7-methoxyquinolin-6-yl)a...)
Affinity DataIC50:  644nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635975((1R,2S)-5'-methoxy-2-(3-{[3-methoxy-6-(oxetan-3-yl...)
Affinity DataIC50:  662nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636040((1R,2S)-2-[3-({2-[(3R)-3-fluoropyrrolidin-1-yl]-5-...)
Affinity DataIC50:  664nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636054((1R,2S)-5'-methoxy-2-(3-{[2-methoxy-6-(morpholine-...)
Affinity DataIC50:  665nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636058((1R,2S)-5'-methoxy-2-{3-[(2-methoxy-5-methylpyrimi...)
Affinity DataIC50:  670nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636103((1R,2S)-5'-methoxy-2-(3-{[2-methoxy-6-(3-oxa-8-aza...)
Affinity DataIC50:  673nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636045((1R,2S)-2-(3-{[2-(3-fluoroazetidin-1-yl)-5-methoxy...)
Affinity DataIC50:  703nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635977((1R,2S)-5'-methoxy-2-(3-{[6-(morpholin-4-yl)-2-(pr...)
Affinity DataIC50:  707nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636109(6-methoxy-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  730nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636134((1R,2S)-2-(3-{[5-(azetidine-1-carbonyl)-3-methoxyp...)
Affinity DataIC50:  737nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636127((1R,2S)-5'-methoxy-2-(3-{[3-methoxy-5-(8-oxa-3-aza...)
Affinity DataIC50:  743nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636089(N,6-dimethoxy-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',...)
Affinity DataIC50:  770nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636065(6-methoxy-5-({6-[(1R,2S)-5'-methoxy-2'-oxo-1',2'-d...)
Affinity DataIC50:  778nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM635914((1R,2S)-2-(3-((6-(1,1-dioxidothiomorpholino)pyrimi...)
Affinity DataIC50:  803nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Oric Pharmaceuticals

US Patent
LigandPNGBDBM636044((1R,2S)-2-(3-{[2-(3,3-difluoroazetidin-1-yl)-5-met...)
Affinity DataIC50:  803nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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