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Found 3 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 7581
TargetComplement factor D [24-253](Homo sapiens (Human))
Novartis Pharma

LigandPNGBDBM171350(1-(2-((1R,3S,5R)-3-((6-Bromopyridin-2-yl)carbamoyl...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:Recombinant human FD (10 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in 0.1 M PBS (pH 7.4) ...More data for this Ligand-Target Pair
TargetComplement factor D [24-253](Homo sapiens (Human))
Novartis Pharma

LigandPNGBDBM171272(1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:Recombinant human FD (10 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in 0.1 M PBS (pH 7.4) ...More data for this Ligand-Target Pair
TargetComplement factor D [24-253](Homo sapiens (Human))
Novartis Pharma

LigandPNGBDBM203865(Methyl (S)-2-((2-((3-(trifluoromethoxy)phenyl)carb...)
Affinity DataIC50:  3.32E+4nMpH: 7.4 T: 2°CAssay Description:Recombinant human FD (10 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in 0.1 M PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB