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Found 74 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 249
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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LigandPNGBDBM142598(US10238658, Example Reference | US10813932, Refere...)
Affinity DataIC50:  45nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247123(3-((4-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50:  111nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247119(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  122nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
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LigandPNGBDBM247099(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  197nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247080(3-((4-((4-(3-(3-(tert-butyl)-1-(4-methylthiophen-2...)
Affinity DataIC50:  207nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247109(3-((4-((4-(3-(3-(tert-butyl)-1-(4-methoxyphenyl)-1...)
Affinity DataIC50:  217nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247107(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  247nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247110(3-((4-((4-(3-(3-(tert-butyl)-1-(3-(2-methoxyethoxy...)
Affinity DataIC50:  281nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247124(1-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(...)
Affinity DataIC50:  282nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247112(3-((4-((4-(3-(3-(tert-butyl)-1-(6-methoxypyridin-3...)
Affinity DataIC50:  283nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247081(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  285nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247059(3-((4-((4-(3-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  286nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247074(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  295nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247073(3-(4-(4-(3-(3-tert-butyl-1-(4-methoxyphenyl)-1H-py...)
Affinity DataIC50:  309nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247083(1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(...)
Affinity DataIC50:  311nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247076(3-((4-((4-(3-(3-isopropyl-1-(4-methoxyphenyl)-1H-p...)
Affinity DataIC50:  317nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247070(3-((6-((4-(3-(3-isopropyl-1-(4-methoxyphenyl)-1H-p...)
Affinity DataIC50:  355nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247077(3-((4-((4-(3-(3-(tert-butyl)-1-(4-methoxyphenyl)-1...)
Affinity DataIC50:  356nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247082(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  390nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247122(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  452nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247068(1-(3-Isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(...)
Affinity DataIC50:  509nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247125(5-((4-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50:  525nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247062(N-(2-(Dimethylamino)ethyl)-3-((4-((4-(3-(3-isoprop...)
Affinity DataIC50:  634nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247069(5-((4-((4-(3-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  672nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247078(3-((4-((4-(3-(3-(3-methyloxetan-3-yl)-1-(p-tolyl)-...)
Affinity DataIC50:  930nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247117(3-bromo-5-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1...)
Affinity DataIC50:  995nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247114(3-methoxy-5-((4-((4-(3-(1-(4-methoxyphenyl)-3-(tet...)
Affinity DataIC50:  1.19E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247097(3-((4-((4-(3-(3-(tert-butyl)-1-(4-methoxyphenyl)-1...)
Affinity DataIC50:  1.20E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247075(3-((4-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50:  1.24E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247058(3-((4-((4-(3-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  1.26E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247096(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  1.34E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247098(3-bromo-5-((4-((4-(3-(3-(tert-butyl)-1-(4-methoxyp...)
Affinity DataIC50: >1.39E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247072(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  1.40E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247061(N-(2-(Dimethylamino)ethyl)-3-((4-((4-(3-(3-isoprop...)
Affinity DataIC50:  1.47E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247101(3-((4-((4-(3-(3-isopropyl-1-(4-methoxyphenyl)-1H-p...)
Affinity DataIC50:  1.63E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247102(3-((4-((4-(3-(3-isopropyl-1-(4-methoxyphenyl)-1H-p...)
Affinity DataIC50:  2.85E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247057(3-((4-((4-(3-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  2.86E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247079(3-((4-((4-(3-(1-(4-methoxyphenyl)-3-(3-methyloxeta...)
Affinity DataIC50:  2.99E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247071(3-((4-((4-(3-(3-isopropyl-1-(4-methoxyphenyl)-1H-p...)
Affinity DataIC50:  3.18E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247085(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  3.21E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247129(3-((6-(4-(3-(3-(tert-Butyl)-1-(4-methoxyphenyl)-1H...)
Affinity DataIC50:  3.52E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247100(3-((4-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50:  3.95E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247126(3-((6-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50:  5.77E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247116(3-chloro-5-((4-((4-(3-(3-isopropyl-1-(4-methoxyphe...)
Affinity DataIC50:  6.94E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247064(3-((4-((4-(3-(3-Isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50:  7.95E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247065(3-Methoxy-N-(2-morpholinoethyl)-5-((4-((4-(3-(3-(p...)
Affinity DataIC50:  8.03E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247113(3-methoxy-5-((4-((4-(3-(1-(4-methoxyphenyl)-3-(tet...)
Affinity DataIC50:  8.47E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247087(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Affinity DataIC50:  9.63E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247063(3-((4-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50: >1.26E+4nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM247103(3-methoxy-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: >1.28E+4nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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