Found 1 Enz. Inhib. hit(s) with all data for assayid = 7 entry = 50042824 TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Entremed
Curated by ChEMBL
Entremed
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Competitive inhibition of human recombinant DOT1L (1 to 416 amino acid residues) using [3H]-SAM assessed as inhibition of nucleosome methylation incu...More data for this Ligand-Target Pair
3D Structure (crystal)