Compile Data Set for Download or QSAR
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Found 14 of affinity data with PDB=1REV
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataIC50:  15.5nMAssay Description:Tested for the inhibition of HIV-1 reverse transcriptase using a ribosomal RNA templateMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50010215(4-Chloro-8-methyl-7-(3-methyl-but-2-enyl)-6,7,8,9-...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration against HIV-1 replication by interfering with virus reverse transcriptaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  200nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  200nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  311nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  7.32E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  1.30E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  3.22E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1868((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...)
Affinity DataIC50:  3.95E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataEC50:  5.60E+3nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 7 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataEC50:  33nMAssay Description:Effective concentration against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataEC50:  60nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair