Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of affinity data with PDB=2BZ5
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM15408(2,5-dichloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50:  700nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM15408(2,5-dichloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM15408(2,5-dichloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50:  700nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM15408(2,5-dichloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as Her2 degradation after 24 hrs by Western blotMore data for this Ligand-Target Pair