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Found 5 of affinity data with PDB=2ZGX
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  140nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM32655(benzamidine- based compound, 4)
Affinity DataKi:  180nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  180nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  180nMAssay Description:Binding affinity to thrombin (unknown origin)More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKd:  110nMAssay Description:Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetryMore data for this Ligand-Target Pair