Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of affinity data with PDB=3CZR
LigandPNGBDBM32573(CHEMBL427896 | arylsulfonylpiperazine, 45)
Affinity DataIC50:  3nM EC50:  57nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM32573(CHEMBL427896 | arylsulfonylpiperazine, 45)
Affinity DataIC50:  3nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
LigandPNGBDBM32574(arylsulfonylpiperazine, 46)
Affinity DataIC50:  29nM EC50:  527nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM32573(CHEMBL427896 | arylsulfonylpiperazine, 45)
Affinity DataIC50:  57nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair