Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of affinity data with PDB=3H3C
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246327(4-(4-((1R,2R)-2-(dimethylamino)cyclopentylamino)-5...)
Affinity DataIC50:  88nMAssay Description:Inhibition of PYK2 by PYK2-LI-COR cellular assayMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246327(4-(4-((1R,2R)-2-(dimethylamino)cyclopentylamino)-5...)
Affinity DataIC50:  140nMAssay Description:Inhibition of PYK2 assessed as reduction in peptide substrate phosphoryltion by fluorimetric methodMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246327(4-(4-((1R,2R)-2-(dimethylamino)cyclopentylamino)-5...)
Affinity DataIC50:  154nMAssay Description:Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair