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Found 4 of affinity data with PDB=3I8V
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50010981((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50010981((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 4 from heart.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50010981((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50010981((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...)
Affinity DataEC50:  3.30E+3nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair