TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of p38 kinaseMore data for this Ligand-Target Pair
3D Structure (crystal)TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of MAPK p38 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 27nMAssay Description:Binding affinity to P38-alpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 27nMAssay Description:Binding constant for full-length p38-alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 495nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 27nMAssay Description:Binding constant for p38-alpha kinase domainMore data for this Ligand-Target Pair
