BindingDB PrimarySearch

Found 3 of affinity data with PDB=3TL5

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

BDBM50358204(CHEMBL1922094)

IC50: 36nMAssay Description:Inhibition of PIK3 gamma-mediated Akt phosphorylation at Ser473 in human PC3 cells by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

BDBM50358204(CHEMBL1922094)

IC50: 36nMAssay Description:Inhibition of PIK3 gamma-mediated Akt phosphorylation at Ser473 in human PC3 cells by ELISAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

BDBM50358204(CHEMBL1922094)

Kd: 2.60nMAssay Description:Binding affinity to human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)