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Found 3 of affinity data with PDB=3TUC
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Pfizer

LigandPNGBDBM92625(Dimethoxyquinoline, 2)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:A Lance TR-FRET assay (Perkin Elmer) was used to measure and compare the potency of compounds against Syk kinase domain.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Pfizer

LigandPNGBDBM92625(Dimethoxyquinoline, 2)
Affinity DataIC50:  100nMAssay Description:Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Pfizer

LigandPNGBDBM92625(Dimethoxyquinoline, 2)
Affinity DataIC50:  100nMAssay Description:Inhibition of Syk (unknown origin) by radiometric assayMore data for this Ligand-Target Pair