BindingDB PrimarySearch_ki

Found 2 of affinity data with PDB=4YKN

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50091689(CHEMBL3582354)

IC50: 8.5nMAssay Description:Inhibition of PI3Kalpha H1047R mutant (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

PNG

BDBM50091689(CHEMBL3582354)

IC50: 10nMAssay Description:Inhibition of wild type his-tagged PI3Kalpha (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)