Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of affinity data with PDB=5FBN
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM267703((R)-4-(8-amino-5-deutero-3-(1-(3-methoxypropanoyl)...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant full-length His6-tagged BTK (unknown origin) expressed in baculovirus infected Sf9 cells using biotinylated A5 peptide as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM267703((R)-4-(8-amino-5-deutero-3-(1-(3-methoxypropanoyl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in anti-IgM-induced MIP1betaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM267703((R)-4-(8-amino-5-deutero-3-(1-(3-methoxypropanoyl)...)
Affinity DataEC50: <10nMpH: 7.2 T: 2°CAssay Description:Btk enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below. Btk enzyme (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB