Compile Data Set for Download or QSAR
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Found 4 of affinity data with PDB=5ICP
TargetCyclin-C(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50191443(CHEMBL3938208)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system preincubat...More data for this Ligand-Target Pair
TargetCyclin-C(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50191354(CHEMBL3934243)
Affinity DataIC50:  17nMAssay Description:Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system preincubat...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50191443(CHEMBL3938208)
Affinity DataIC50:  70nMAssay Description:Inhibition of CDK8 in human 7dF3 cells preincubated for 2 hrs followed by beta-oestradiol addition measured after 24 hrs by luciferase reporter gene ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50191354(CHEMBL3934243)
Affinity DataIC50:  100nMAssay Description:Inhibition of CDK8 in human 7dF3 cells preincubated for 2 hrs followed by beta-oestradiol addition measured after 24 hrs by luciferase reporter gene ...More data for this Ligand-Target Pair