Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of affinity data with PDB=5M6U
LigandPNGBDBM50208166(CHEMBL3901527)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of recombinant human N-terminal His-tagged full length p110delta/recombinant human full length p85alpha using PIP2 as substrate preincubat...More data for this Ligand-Target Pair
LigandPNGBDBM50208166(CHEMBL3901527)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PI3K p110delta/human p85alpha expressed in baculovirus infected sf21 cells using P...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50208166(CHEMBL3901527)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of PI3Kdelta in human THP1 cells assessed as reduction in MCSF-stimulated akt phosphorylation at Thr308 preincubated for 30 mins followed ...More data for this Ligand-Target Pair
LigandPNGBDBM50208166(CHEMBL3901527)
Affinity DataIC50:  640nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length p110beta/recombinant human full length p85alpha using PIP2 as substrate preincubat...More data for this Ligand-Target Pair
LigandPNGBDBM50208166(CHEMBL3901527)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length p110alpha/recombinant human full length p85alpha using PIP2 as substrate preincuba...More data for this Ligand-Target Pair