TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human TAF1 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre (Nrc)
Curated by ChEMBL
National Research Centre (Nrc)
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human GST-tagged TAF1 BD2 (1519 to 1651 residues) expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 preincubated for 15 mins followed ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKd: 99nMAssay Description:Binding affinity to human GST-tagged TAF1 BD2 (1519 to 1651 residues) expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 by ITCMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKd: 87nMAssay Description:Inhibition of Halo-tagged histone H4 binding to C-terminally NanoLuc luciferase conjugated human TAF1 BD2 (1528 to 1640 residues) expressed in human ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human GST-tagged TAF1 BD2 (1519 to 1651 residues) expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 preincubated for 15 mins followed ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to C-terminally NanoLuc luciferase conjugated human TAF1 BD2 (1528 to 1640 residues) expressed in huma...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKd: 73nMAssay Description:Inhibition of human GST-tagged TAF1 BD2 (1519 to 1651 residues) expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 preincubated for 15 mins followed ...More data for this Ligand-Target Pair
