BindingDB PrimarySearch

Found 1 of affinity data with PDB=5SXK

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Johns Hopkins University School Of Medicine

Curated by ChEMBL

BDBM74255((3-amino-2-methyl-phenyl)amine | 1,3-Benzenediamin...)

IC50: 2.00E+4nMAssay Description:Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation using PIP2 as substrate after 45 mins by fluorescence po...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)