TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Saint Petersburg State University
Curated by ChEMBL
Saint Petersburg State University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of IDH1 R132H mutant in human HCT116 cells assessed as reduction in 2-HG level after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Saint Petersburg State University
Curated by ChEMBL
Saint Petersburg State University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin)More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Saint Petersburg State University
Curated by ChEMBL
Saint Petersburg State University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair