Compile Data Set for Download or QSAR
maximum 50k data
Found 2 of affinity data with PDB=5USQ
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238094(CHEMBL4096361)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant N-terminal GST tagged human ALK5 (200 to 503 residues) expressed in baculovirus expression system using FAM-NH2-KVLTQMGSPSI...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50238094(CHEMBL4096361)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in SBE-bla HEK293T cells assessed as decrease in TGFbeta1-induced Smad2/3 phosphorylation by beta lacta...More data for this Ligand-Target Pair