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Found 5 of affinity data with PDB=5V82
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM249028(US9434725, 259 | US9434725, 271 | US9434725, 272)
Affinity DataKi:  0.0530nM ΔG°:  -58.7kJ/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM249028(US9434725, 259 | US9434725, 271 | US9434725, 272)
Affinity DataKi:  0.0670nM ΔG°:  -58.1kJ/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM249028(US9434725, 259 | US9434725, 271 | US9434725, 272)
Affinity DataKi:  0.189nM ΔG°:  -55.5kJ/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Mus musculus (Mouse))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM249028(US9434725, 259 | US9434725, 271 | US9434725, 272)
Affinity DataIC50:  194nMAssay Description:BaF3, a murine interleukin-3 dependent pro-B cell line, parental cells, BaF3 PIM1 cells, BaF3 PIM2 cells, and MM1.S (multiple myeloma) cells were see...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase pim-1(Mus musculus (Mouse))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM249028(US9434725, 259 | US9434725, 271 | US9434725, 272)
Affinity DataIC50:  1.40E+3nMAssay Description:BaF3, a murine interleukin-3 dependent pro-B cell line, parental cells, BaF3 PIM1 cells, BaF3 PIM2 cells, and MM1.S (multiple myeloma) cells were see...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB