Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of affinity data with PDB=5W4R
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)
Affinity DataIC50:  46nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)
Affinity DataIC50:  46nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)
Affinity DataKd:  20nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)
Affinity DataKd:  20nMAssay Description:Displacement of 1,8-ANS from human N-terminal His-tagged RORgammat LBD (850 to 1635 residues) expressed in Escherichia coli by thermofluor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)
Affinity DataKd:  33nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)
Affinity DataKd:  18nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)
Affinity DataKd:  20nMAssay Description:Displacement of 1,8-ANS from human N-terminal His-tagged RORgammat LBD (850 to 1635 residues) expressed in Escherichia coli by thermofluor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB