Compile Data Set for Download or QSAR
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Found 3 of affinity data with PDB=5WO4
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50250927(CHEMBL4071005 | US10766883, Ex-1)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50250927(CHEMBL4071005 | US10766883, Ex-1)
Affinity DataIC50:  13nMAssay Description:Inhibition of JAK1 in IL6-stimulated human ME180 cells expressing stably integrated beta-lactamase reporter gene under control of sis-inducible eleme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50250927(CHEMBL4071005 | US10766883, Ex-1)
Affinity DataIC50:  1.76E+3nMAssay Description:Displacement of [35S]-MK499 from human ERG expressed in HEK293 cell membranesMore data for this Ligand-Target Pair