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Found 3 of affinity data with PDB=8JD0
LigandPNGBDBM212969(US9278960, 4-53 | US9663506, Example 4-53)
Affinity DataIC50:  25nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212969(US9278960, 4-53 | US9663506, Example 4-53)
Affinity DataIC50:  25nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212969(US9278960, 4-53 | US9663506, Example 4-53)
Affinity DataIC50:  25nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB