Compile Data Set for Download or QSAR
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Found 14 of affinity data with PDB=8JD6
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataKi:  2.30E+3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4 [Q124R](Rattus norvegicus)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  295nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human mGlu4 receptor assessed as increase in calcium flux by Fluo-4 AM dye based analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  330nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  290nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  1.30E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  4.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux prein...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4 [Q124R](Rattus norvegicus)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  9.84E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptom...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  1.09E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50293743(CHEMBL556667 | N-(3-chlorophenyl)picolinamide | ci...)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptorMore data for this Ligand-Target Pair