Affinity DataKi: 1.20nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Competitive inhibition of Escherichia coli Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
Affinity DataKi: 114nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
Affinity DataKi: 213nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.55E+4nM ΔG°: -24.4kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nM ΔG°: -24.1kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 5.88E+4nM ΔG°: -23.7kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 5.30E+5nM ΔG°: -18.4kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+5nM ΔG°: -18.2kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+6nM ΔG°: -16.3kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 1.67E+6nM ΔG°: -15.6kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+6nM ΔG°: -15.1kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+6nM ΔG°: -14.6kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+6nM ΔG°: -14.6kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 3.33E+6nM ΔG°: -13.9kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 3.33E+6nM ΔG°: -13.9kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+6nM ΔG°: -12.9kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+6nM ΔG°: -12.9kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+6nM ΔG°: -12.9kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 8.33E+6nM ΔG°: -11.7kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+7nM ΔG°: -10.7kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+7nM ΔG°: -10.7kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 1.43E+7nM ΔG°: -10.4kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 1.67E+7nM ΔG°: -9.98kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataKi: 1.67E+7nM ΔG°: -9.98kJ/molepH: 7.5 T: 2°CAssay Description:Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 265nMAssay Description:Inhibitory concentration against Escherichia coli Ile-tRNA synthetase More data for this Ligand-Target Pair
Affinity DataIC50: 494nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory concentration against Escherichia coli Ile-tRNA synthetase More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory concentration against Escherichia coli Ile-tRNA synthetase More data for this Ligand-Target Pair
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.17E+4nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibitory concentration against Escherichia coli Ile-tRNA synthetase More data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+5nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.43E+5nMAssay Description:Inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair