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Found 266
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50552138(CHEMBL3935646)
Affinity DataKi:  410nMAssay Description:Inhibition of rhodamine-labeled Pam3CSK4 binding to TLR1 (unknown origin)/TLR2 (unknown origin) expressed in baculovirus infected sf9 cells incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50552135(CHEMBL4303210)
Affinity DataIC50:  54nMAssay Description:Inhibition of Rho-Pam3 binding to TLR1 (unknown origin)/human TLR2 expressed in HEK293 cells incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50543142(CHEMBL4641633)
Affinity DataIC50: >6.50E+3nMAssay Description:Antagonist activity at TLR1 in human PBMC assessed as inhibition of Pam3CSK4-induced TNFalpha production preincubated for 30 mins followed by Pam3CSK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50463543(CHEMBL4249593)
Affinity DataIC50:  4.58E+4nMAssay Description:Antagonist activity at FLAG-tagged human TLR2/TLR1 expressed in HEK293 cells co-expressing pGL3-Elam.luc assessed as inhibition of Pam3CSK4-stimulate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR1/2 in human THP-1 cells assessed as increase in TNF-alpha release incubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50406615(CHEMBL5277772)
Affinity DataEC50:  2.51E+3nMAssay Description:Blocking 5-HT2A receptor-mediated contractions of rat tail arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50552135(CHEMBL4303210)
Affinity DataEC50:  5.20E+3nMAssay Description:Blocking 5-HT2A receptor-mediated contractions of rat tail arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50406629(CHEMBL5272597)
Affinity DataEC50: >5.00E+3nMAssay Description:Blocking 5-HT2A receptor-mediated contractions of rat tail arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50511993(CHEMBL4472879)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600847(CHEMBL5179242)
Affinity DataEC50:  200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600848(CHEMBL5190772)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600849(CHEMBL5176430)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600850(CHEMBL5206865)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600851(CHEMBL5183767)
Affinity DataEC50:  45nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600852(CHEMBL5199615)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600853(CHEMBL5172955)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600854(CHEMBL5201018)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600855(CHEMBL5182057)
Affinity DataEC50:  90nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600856(CHEMBL5201843)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600857(CHEMBL5177664)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600858(CHEMBL5206661)
Affinity DataEC50:  1nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600859(CHEMBL5195614)
Affinity DataEC50:  20nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600860(CHEMBL5184441)
Affinity DataEC50:  200nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600861(CHEMBL5188206)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600862(CHEMBL5172228)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600863(CHEMBL5196512)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600864(CHEMBL5179849)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600865(CHEMBL5205616)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600866(CHEMBL5207112)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600867(CHEMBL5180346)
Affinity DataEC50:  7nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600868(CHEMBL5179296)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600869(CHEMBL5207926)
Affinity DataEC50:  2nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600870(CHEMBL5181859)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600871(CHEMBL5201759)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600872(CHEMBL5205549)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600873(CHEMBL5172090)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600874(CHEMBL5188866)
Affinity DataEC50:  40nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600875(CHEMBL5191310)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600876(CHEMBL5188570)
Affinity DataEC50:  100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600877(CHEMBL5203424)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600878(CHEMBL5169343)
Affinity DataEC50:  0.25nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600879(CHEMBL5188254)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600880(CHEMBL5181631)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600881(CHEMBL5185917)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600882(CHEMBL5180856)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600883(CHEMBL5181114)
Affinity DataEC50:  56nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600884(CHEMBL5193298)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600885(CHEMBL5187007)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600886(CHEMBL5203059)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetToll-like receptor 1(Homo sapiens)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50600887(CHEMBL5191877)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at TLR1/TLR2 in human THP-1 derived macrophages assessed as stimulation of TNF alpha release measured for 4 hrs by ELISA based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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