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Found
1
Enz. Inhib. hit(s) for PDB:
2I0H
Target
Mitogen-activated protein kinase 14
(Mouse)
Merck Research Laboratories
Ligand
BDBM16525
(2-{3-[(2-chloro-4-fluorophenyl)[1-(2-chlorophenyl)...)
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Affinity Data
IC50: 9nM
pH: 7.0 T: 2°C
Assay Description:
The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...
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Target Info
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Ligand Info
PC cid
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In Depth
Date in BDB:
7/17/2007
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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