Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 2OW9
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 30nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MMP13 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asp270 residues) using acetyl-Pro-Leu-Gly-[2-mercapto-4-methyl-pentanoyl]-Leu-Gly-O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant full length MMP13-mediated type 2 collagen cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[...)
Affinity DataKi:  64nMAssay Description:Inhibition of human recombinant full length MMP13 by steady state kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)